Knowledge Centre

There are a variety of reasons why we may need to prepare a sample before it can be analyzed, some of the most common reasons are cleaning up the sample, increasing the concentration of the target analyte, switching the sample solvent or matrix and derivatization of the analyte.

Solid phase extraction (SPE) is a technique that is used to clean up and concentrate samples prior to analysis by gas chromatography (GC) or high performance liquid chromatography (HPLC). This often involves the use of SPE cartridges which are cartridges that contain a chromatographic sorbent bed, the analytes will remain on the sorbent bed and the sample matrix liquid will

LLE is perhaps one of the oldest and most widely used sample extraction techniques, it has applications across many different industries including pharmaceutical, pesticide and forensics. LLE can also be used in the environmental and food industries for numerous applications – such as the analysis of semi-volatile organic compounds.

Derivatization extraction can increase the detectability of the target analyte. It is also able to allow for the analysis of compounds which are not directly amenable because they may have inadequate volatility or stability.

The INFRA group is one of the most important manufacturers of industrial gases in the world. Recently we had the opportunity to connect with David Ortega, the Quality Control Lab Manager at INFRA, who shared insights into his experience with our SCION.

Recently we had the opportunity to connect with our customers at ENLink Midstream. We caught up with Joseph Durocher, one of their lab technicians who shared insights into their experience using and working with SCION Instruments.

When validating an analytical method it is highly likely that analyte confirmation will be required for either active ingredients(s) and/or impurities present within the sample. Discover an alternative to mass spec analyte confirmation in this technical note.

Understanding the concepts of accuracy and precision is crucial in analytical method development and laboratory practices. This technical note outlines the difference between the two measurements, and explores various ways to enhance both accuracy and precision.

The following guide will focus on application markets, detailing the various different application markets, target compound types and associated separation modes. When selecting a column for a particular application, use the guide as a reference for identifying the separation mode to be used. This is the first step in choosing the right column for the desired application

In our HPLC column selection guide we provide a comparison of the following columns and their features: Reverse Phase Chromatography Columns, Polymer Based Hydrophilic Interaction Chromatography (HILIC) Columns, Silica Based Reverse Phase Chromatography Columns (ODS), Silica Based Normal Phase Chromatography and HILIC Columns.