ResourcesApplication Notes

Showing 1 - 10 of 138 results

Residual Solvent Analysis of Chemical Products by GC-FID with Hydrogen as a Carrier Gas

In this application note we will successfully validate a method for the analysis of residual solvents by GC-FID. A technical grade active ingredient (eugenol) will also be tested.

Active Pharmaceutical Ingredients Qualitative Analysis by GC-MS

Analysis of APIs is important to provide quality assurance and regulatory compliance with authorities such as U.S. Food and Drug Administration (FDA) or European Medicines Agency (EMA). This application note emphasizes the qualitative examination of the specified antihistamines through the analysis of both standards and samples and samples, including antihistamines, paracetamol, and ibuprofen. The identification process is supported by comparing the spectral characteristics between standards and samples, as well as using a library matching approach.

Plant Protection Products Impurity Assay by GC-FID with Hydrogen Carrier Gas

In this application note we will validate and assay for the relevant impurity methyl eugenol and an example significant impurity 4-(prop-2-en-1-yl)phenol. For ease we will refer to methyl eugenol as impurity 1 and 4-(prop-2-en-1-yl)phenol as impurity 2 from here on.

Plant Protection Products Impurity Screening by GC-FID with GC-MS Confirmation

Determining impurity content is a requirement across many regulated industries from pharmaceutical, food, agriculture, and environmental. But how do we decide which impurities are present within a product? Often chemical products can be very complex with dozens of impurities present, do we need to measure them all, or can we discount some, how do we decide this? In this application note we will discuss how to determine which impurities should be identified and accurately quantified to satisfy regulatory requirements.

The Use of Alternative Carrier Gases in Gas Chromatography

With the ongoing helium shortage affecting GC users – this app note provides a comparison of the carrier gas alternatives: nitrogen and hydrogen.

Plant Protection Products Active Ingredient Assay by GC-FID with Nitrogen Carrier Gas

An active ingredient (AI) is the component of a chemical product which produces the desired chemical or biological effect. In this application note we will discover how to validate a method and assay for the AI content of a plant protection product (PPP).

Cannabis Potency by GC-FID with Carrier Gas Comparison (Helium, Hydrogen, Nitrogen)

Due to the legalization of cannabis in multiple countries for medicinal or recreational use, there has been an increased demand for quality control of hemp and marijuana products. This is to ensure the product labels accurately reflect the characteristics and quality of the flood of new products entering the market. SCION 8300 GC and 8500 GC platforms are ideally equipped to meet the analysis needs of the Cannabis industry.

IP480 Determination of Boiling Range Distribution of Middle Distillates and Lubricating Base Oils - Gas Chromatography Method

SCION Instruments offers the solution for a simulated distillation of middle distillates and lubricating base oils. In our latest Application Note, discover how the 8500 and 8300 GC platforms can be used for safer and more efficient simulated distillations.

EN15199-1 Determination of Boiling Range Distribution by Gas Chromatography Method Part 1: Middle Distillates and Lubricating Base Oils

The SCION Instruments 8X00 GC-platform provides a robust and complete solution for the simulated distillation of distillates and lubricating base oils, following standardized method EN15199-1. This Application Note demonstrate that this method and the SCION Instruments GC system configuration performs excellent and meets all the specifications mentioned in EN15199-1.

A Comparative Analysis of Fuel Oxygenates in Soil by Dynamic and Static Headspace Utilizing the HT3 Automatic Headspace Analyzer

Fuel oxygenates have been added to gasoline for years to produce more efficient and cleaner fuel combustion thus reducing pollution. Unfortunately, since gasoline is stored in large storage tanks that are either above or below ground, fuel oxygenates can leach into the surrounding water or soil causing contamination and possible health risks to the surrounding environment. This application note presents methods for Gas Chromatograph/Mass Spectrometer (GC/MS) to analyze fuel oxygenates in a soil matrix.