February 13, 2024
In this application note we will successfully validate a method for the analysis of residual solvents by GC-FID. A technical grade active ingredient (eugenol) will also be tested.
January 31, 2024
Analysis of APIs is important to provide quality assurance and regulatory compliance with authorities such as U.S. Food and Drug Administration (FDA) or European Medicines Agency (EMA). This application note emphasizes the qualitative examination of the specified antihistamines through the analysis of both standards and samples and samples, including antihistamines, paracetamol, and ibuprofen. The identification process is supported by comparing the spectral characteristics between standards and samples, as well as using a library matching approach.
January 17, 2024
In this application note we will validate and assay for the relevant impurity methyl eugenol and an example significant impurity 4-(prop-2-en-1-yl)phenol. For ease we will refer to methyl eugenol as impurity 1 and 4-(prop-2-en-1-yl)phenol as impurity 2 from here on.
December 7, 2023
Determining impurity content is a requirement across many regulated industries from pharmaceutical, food, agriculture, and environmental. But how do we decide which impurities are present within a product? Often chemical products can be very complex with dozens of impurities present, do we need to measure them all, or can we discount some, how do we decide this? In this application note we will discuss how to determine which impurities should be identified and accurately quantified to satisfy regulatory requirements.
October 19, 2023
With the ongoing helium shortage affecting GC users – this app note provides a comparison of the carrier gas alternatives: nitrogen and hydrogen.
September 19, 2023
An active ingredient (AI) is the component of a chemical product which produces the desired chemical or biological effect. In this application note we will discover how to validate a method and assay for the AI content of a plant protection product (PPP).
May 18, 2023
Due to the legalization of cannabis in multiple countries for medicinal or recreational use, there has been an increased demand for quality control of hemp and marijuana products. This is to ensure the product labels accurately reflect the characteristics and quality of the flood of new products entering the market. SCION 8300 GC and 8500 GC platforms are ideally equipped to meet the analysis needs of the Cannabis industry.
December 6, 2022
SCION Instruments offers the solution for a simulated distillation of middle distillates and lubricating base oils. In our latest Application Note, discover how the 8500 and 8300 GC platforms can be used for safer and more efficient simulated distillations.
November 28, 2022
The SCION Instruments 8X00 GC-platform provides a robust and complete solution for the simulated distillation of distillates and lubricating base oils, following standardized method EN15199-1. This Application Note demonstrate that this method and the SCION Instruments GC system configuration performs excellent and meets all the specifications mentioned in EN15199-1.
November 21, 2022
Fuel oxygenates have been added to gasoline for years to produce more efficient and cleaner fuel combustion thus reducing pollution. Unfortunately, since gasoline is stored in large storage tanks that are either above or below ground, fuel oxygenates can leach into the surrounding water or soil causing contamination and possible health risks to the surrounding environment. This application note presents methods for Gas Chromatograph/Mass Spectrometer (GC/MS) to analyze fuel oxygenates in a soil matrix.