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GC-MS Method Development Webinar

Method development SQ

GC-MS method development ensures that analytical assays are accurate, precise, and reliable. This begins with a thorough understanding of the sample. With our MS you can search via the library search tool used to identify unknown compounds. A mass spectrum acts like a fingerprint for a compound, by comparing the spectrum of an unknown compound to a database, you can identify the compound based on the best match.

After retrieving the sample data through the library search, the method can be set to Selective Ion Monitoring (SIM) mode, using quantifier and qualifier ions to achieve higher sensitivity and more accurate result

Validating the method is crucial to ensure its reliability and confidence. This validation process may be guided by relevant documentation or regulatory standards.

Key learnings:

  • What is Fullscan? How does it work in MSWS?
  • What is Selected Ion Monitoring, how to use it in MSWS.
  • How can you choose quantifier and qualifier ions?
  • SCION Instruments NIST library search tool.
  • Using Electron Ionization (EI) or Chemical Ionization.

 

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