Gas Chromatography GC Troubleshooting Guide

Introducing our Gas Chromatography Troubleshooting Guide – your go-to resource for resolving challenges and optimizing performance in gas chromatography (GC) analyses.

Indications of errors with the system or method? 

• Changes in peak shape/height (different than what was expected/known) 
• Changes in retention time (other than expected change from cutting column during installation) 
• Instability of the baseline 
• Asymmetrical peak shapes, non-Gausian 
• Any unusual behavior of expected peaks 

Top Tips to Restore your Chromatography: 

1. Split peaks (multiple peaks corresponding to a single compound) 

2. Peak tailing

3. Peak fronting

4.Peak broadening/Poor resolution

5. Appearance of ghost peaks

6. Long solvent peak tail

7. No sample peak/Low response

8. Extreme baseline increase during temperature programming

9. High boiling compound not eluting (C60 to C80)

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