Knowledge Centre

Samples that are to be analysed by GC-MS often contain dirty compounds that sometimes require ‘specialist’ sample preparation as detailed in this guide.

Analyte confirmation can be specified as a requirement for method validation to ensure that compounds during the analysis have been correctly identified. This can be important across many industries to ensure active ingredient(s) and/ or impurities within a sample can be validated as the purity or identity they have been described as for both safety and quality control.

Solid phase extraction (SPE) is a powerful sample preparation technique used across many different industries including pharmaceutical, environmental and forensics. The main aims of sample preparation is to remove or minimise sample matrix effects.

Mass spectrometry analysis requires an internal standard (IS) to ensure accurate quantitation and to correct for various sources of variability that can affect the results. 

Biodiesel analysis is essential for ensuring fuel quality, engine performance, environmental compliance, and consumer safety. Proper testing identifies impurities, enhances fuel efficiency, and helps prevent engine damage.  

Soil composition directly affects the quality and usability of soil which is why analyzing substances within soil demands precise methods. Soil pollution arises from both natural and human activities, including volcanic eruptions, soil erosion, continental dust, and urban runoff.

Selecting the right column depends on several key factors, including your application market, base material, functional group, and separation mode. Therefore, understanding these elements is essential for achieving the best analytical results.

GC columns can generally be split into two categories: packed columns and capillary columns. Depending on your application, this will influence the type of GC column you need and the specifications of the column in that category.

Choosing the correct liner is crucial because it facilitates the transfer of the sample to the GC column. It can significantly influence the accuracy of the analysis.

Matrix spiking is a technique used in analytical chemistry to evaluate the performance of an analytical method for a specific sample type (matrix).