EPA Method 8141B Organophosphorus Compounds by GC-NPD

Monitoring organophosphorus pesticides in water is essential to protect human health and ensure regulatory compliance. This application note demonstrates the analysis of organophosphorus (OP) compounds in water in accordance with US EPA Method 8141B, using gas chromatography with a nitrogen-phosphorus detector (GC-NPD). The method, performed on a SCION 8500 GC with an 8400 PRO autosampler, delivers excellent linearity, sensitivity, and system precision across a wide range of OP pesticides. The study highlights practical sample preparation, method validation using internal standards, and performance evaluation through QC spiked samples, providing a reliable approach for routine pesticide monitoring in water matrices.

Key learnings from this application note :

  1. Discover how using SCION instruments’ GC-NPD can be used to analyze organophosphorus pesticides following EPA Method 8141B.
  2. Learn how liquid-liquid extraction can be used as a sample preparation technique to prepare water samples for GC analysis.
  3. Understand the importance of spiking samples to calculate recovery in order to evaluate the performance of the analytical method to ensure accurate and valid results.

Download this Application Note –  EPA Method 8141B Organophosphorus Compounds by Gas Chromatography (GC-NPD)